20 research outputs found
MINIMIZATION OF RESOURCE UTILIZATION FOR A REAL-TIME DEPTH-MAP COMPUTATIONAL MODULE ON FPGA
Depth-map algorithm allows camera system to estimate depth in many applications. The algorithm is computationally intensive and therefore more effective to be implemented on hardware such as the Field Programmable Gate Array (FPGA). However, the recurring issue in FPGA implementation is the resource limitation. The issue is normally resolved by modifying the algorithm. However, the issue can also be addressed by implementing hardware architectures without the need to modify the depth-map algorithm. In this thesis, five different depth-map processor architectures for the sum-of-absolute-difference (SAD) depth-map algorithm on FPGA at real-time were designed and implemented. Two resource minimization techniques were employed to address the resource limitation issues. Resource usage and performance of these architectures were compared. Memory contention and bandwidth constrain were resolved by using self-initiative memory controller, FIFOs and line buffers. Parallel processing was utilized to achieve high processing speed at low clock frequency. Memory-based line buffers were used instead of register-based line buffers to save 62.4% of logic element (LEs) used, but require some additional dedicated memory bits. A proper use of registers to replace repetitive subtractors saves 24.75% of LEs. The system achieves SAD performance of 295 mega pixel disparity per second (MPDS) for the architecture with 640x480 pixel image, 3x3 pixel window size, 32 pixel disparity range and 30 frames per second. The system achieves SAD performance of 590 MPDS for the 64 pixels disparity range architecture. The disparity matching module works at the frequency of 10 MHz and produces one pixel of result every clock cycle. The results are dense disparity images, suitable for high speed, low cost, low power applications
MINIMIZATION OF RESOURCE UTILIZATION FOR A REAL-TIME DEPTH-MAP COMPUTATIONAL MODULE ON FPGA
Depth-map algorithm allows camera system to estimate depth in many applications. The algorithm is computationally intensive and therefore more effective to be implemented on hardware such as the Field Programmable Gate Array (FPGA). However, the recurring issue in FPGA implementation is the resource limitation. The issue is normally resolved by modifying the algorithm. However, the issue can also be addressed by implementing hardware architectures without the need to modify the depth-map algorithm. In this thesis, five different depth-map processor architectures for the sum-of-absolute-difference (SAD) depth-map algorithm on FPGA at real-time were designed and implemented. Two resource minimization techniques were employed to address the resource limitation issues. Resource usage and performance of these architectures were compared. Memory contention and bandwidth constrain were resolved by using self-initiative memory controller, FIFOs and line buffers. Parallel processing was utilized to achieve high processing speed at low clock frequency. Memory-based line buffers were used instead of register-based line buffers to save 62.4% of logic element (LEs) used, but require some additional dedicated memory bits. A proper use of registers to replace repetitive subtractors saves 24.75% of LEs. The system achieves SAD performance of 295 mega pixel disparity per second (MPDS) for the architecture with 640x480 pixel image, 3x3 pixel window size, 32 pixel disparity range and 30 frames per second. The system achieves SAD performance of 590 MPDS for the 64 pixels disparity range architecture. The disparity matching module works at the frequency of 10 MHz and produces one pixel of result every clock cycle. The results are dense disparity images, suitable for high speed, low cost, low power applications
Spatiotemporal evolution of SARS-CoV-2 Alpha and Delta variants during large nationwide outbreak of COVID-19, Vietnam, 2021
We analyzed 1,303 SARS-CoV-2 whole-genome sequences from Vietnam, and found the Alpha and Delta variants were responsible for a large nationwide outbreak of COVID-19 in 2021. The Delta variant was confined to the AY.57 lineage and caused >1.7 million infections and >32,000 deaths. Viral transmission was strongly affected by nonpharmaceutical interventions
Safety and efficacy of fluoxetine on functional outcome after acute stroke (AFFINITY): a randomised, double-blind, placebo-controlled trial
Background
Trials of fluoxetine for recovery after stroke report conflicting results. The Assessment oF FluoxetINe In sTroke recoverY (AFFINITY) trial aimed to show if daily oral fluoxetine for 6 months after stroke improves functional outcome in an ethnically diverse population.
Methods
AFFINITY was a randomised, parallel-group, double-blind, placebo-controlled trial done in 43 hospital stroke units in Australia (n=29), New Zealand (four), and Vietnam (ten). Eligible patients were adults (aged ≥18 years) with a clinical diagnosis of acute stroke in the previous 2–15 days, brain imaging consistent with ischaemic or haemorrhagic stroke, and a persisting neurological deficit that produced a modified Rankin Scale (mRS) score of 1 or more. Patients were randomly assigned 1:1 via a web-based system using a minimisation algorithm to once daily, oral fluoxetine 20 mg capsules or matching placebo for 6 months. Patients, carers, investigators, and outcome assessors were masked to the treatment allocation. The primary outcome was functional status, measured by the mRS, at 6 months. The primary analysis was an ordinal logistic regression of the mRS at 6 months, adjusted for minimisation variables. Primary and safety analyses were done according to the patient's treatment allocation. The trial is registered with the Australian New Zealand Clinical Trials Registry, ACTRN12611000774921.
Findings
Between Jan 11, 2013, and June 30, 2019, 1280 patients were recruited in Australia (n=532), New Zealand (n=42), and Vietnam (n=706), of whom 642 were randomly assigned to fluoxetine and 638 were randomly assigned to placebo. Mean duration of trial treatment was 167 days (SD 48·1). At 6 months, mRS data were available in 624 (97%) patients in the fluoxetine group and 632 (99%) in the placebo group. The distribution of mRS categories was similar in the fluoxetine and placebo groups (adjusted common odds ratio 0·94, 95% CI 0·76–1·15; p=0·53). Compared with patients in the placebo group, patients in the fluoxetine group had more falls (20 [3%] vs seven [1%]; p=0·018), bone fractures (19 [3%] vs six [1%]; p=0·014), and epileptic seizures (ten [2%] vs two [<1%]; p=0·038) at 6 months.
Interpretation
Oral fluoxetine 20 mg daily for 6 months after acute stroke did not improve functional outcome and increased the risk of falls, bone fractures, and epileptic seizures. These results do not support the use of fluoxetine to improve functional outcome after stroke
FDG-avid portal vein tumor thrombosis from hepatocellular carcinoma in contrast-enhanced FDG PET/CT
Objective(s): In this study, we aimed to describe the characteristics of portal
vein tumor thrombosis (PVTT), complicating hepatocellular carcinoma (HCC)
in contrast-enhanced FDG PET/CT scan.
Methods: In this retrospective study, 9 HCC patients with FDG-avid PVTT
were diagnosed by contrast-enhanced fluorodeoxyglucose positron emission
tomography/computed tomography (FDG PET/CT), which is a combination
of dynamic liver CT scan, multiphase imaging, and whole-body PET scan.
PET and CT DICOM images of patients were imported into the PET/CT
imaging system for the re-analysis of contrast enhancement and FDG uptake
in thrombus, the diameter of the involved portal vein, and characteristics of
liver tumors and metastasis.
Results: Two patients with previously untreated HCC and 7 cases with previously
treated HCC had FDG-avid PVTT in contrast-enhanced FDG PET/CT scan. During
the arterial phase of CT scan, portal vein thrombus showed contrast enhancement
in 8 out of 9 patients (88.9%). PET scan showed an increased linear FDG uptake
along the thrombosed portal vein in all patients. The mean greatest diameter of
thrombosed portal veins was 1.8 ± 0.2 cm, which was significantly greater than
that observed in normal portal veins (P<0.001). FDG uptake level in portal vein
thrombus was significantly higher than that of blood pool in the reference normal
portal vein (P=0.001). PVTT was caused by the direct extension of liver tumors.
All patients had visible FDG-avid liver tumors in contrast-enhanced images. Five
out of 9 patients (55.6%) had no extrahepatic metastasis, 3 cases (33.3%) had
metastasis of regional lymph nodes, and 1 case (11.1%) presented with distant
metastasis. The median estimated survival time of patients was 5 months.
Conclusion: The intraluminal filling defect consistent with thrombous within
the portal vein, expansion of the involved portal vein, contrast enhancement,
and linear increased FDG uptake of the thrombus extended from liver tumor
are findings of FDG-avid PVTT from HCC in contrast-enhanced FDG PET/CT
FDG-Avid Portal Vein Tumor Thrombosis from Hepatocellular Carcinoma in Contrast-Enhanced FDG PET/CT
In this study, we aimed to describe the characteristics of portal vein tumor thrombosis (PVTT), complicating hepatocellular carcinoma (HCC) in contrast-enhanced FDG PET/CT scan
Blood Pressure Control and Associations with Social Support among Hypertensive Outpatients in a Developing Country
Relationships between social support characteristics with blood pressure control and recommended behaviors in Vietnamese hypertensive patients have not been investigated. This study is aimed at examining the role of social support characteristics in hypertension control and behaviors. Patients with hypertension (n=220) in Hanoi, Vietnam, were recruited into a cross-sectional study. Both functional and structural characteristics of social support and network were examined. Results showed that increasing total network size was related to 52% higher odds of uncontrolled hypertension (adjusted OR=1.52, 95%CI=1.22−1.89). Higher network sizes on the provision of information support related to advice, emotional support related to decisions, and practical support related to sickness were associated with lower odds of uncontrolled hypertension. Every additional 1% of the percentage of network members having hypertension decreased 2% the odds of uncontrolled hypertension (adjusted OR=0.98, 95%CI=0.96−1.00). A 1% additional network members who were living in the same household was associated with a decrease of 0.08 point of behavioral adherence score (coef.=−0.08; 95%CI=−0.12−0.03). Meanwhile, a 1% increase of network members who were friends on the provision of practical support related to sickness and jobs was related to an increase of 0.10 point and 0.19 point of behavioral adherence score (coef.=0.10; 95%CI=0.04−0.17 and coef.=0.19; 95%CI=0.06−0.32, respectively). The current study suggested that further interventions to improve hypertension management should address the potential effects of social network characteristics